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5-Fluorouracil

Chemical Structure : 5-Fluorouracil

CAS No.: 51-21-8

5-Fluorouracil (5-FU;Fluorouracil)

Catalog No.: PC-46012Not For Human Use, Lab Use Only.

An uridine analog that is a widely used chemotherapeutic agent.

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Biological Activity

An uridine analog that is a widely used chemotherapeutic agent; affects pyrimidine synthesis by inhibiting thymidylate synthase (TS), inhibits DNA/RNA synthesis in cancer cells.

Chemotherapeutic Agents

Approved

Physicochemical Properties

M.Wt 130.0772
Formula C4H3FN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 15 mg/mL

Chemical Name/SMILES

2,4(1H,3H)-Pyrimidinedione, 5-fluoro-

References

1. Longley DB, et al. Nat Rev Cancer. 2003 May;3(5):330-8.

2. Sugamura K, et al. Cancer. 1997 Jan 1;79(1):12-7.

3. Shchepotin IB, et al. Anticancer Res. 1994 May-Jun;14(3A):1027-31.

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