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Chemical Structure : AAI-101
Catalog No.: PC-61972Not For Human Use, Lab Use Only.
AAI-101 is a novel extended-spectrum β-lactamase inhibitor with activity against many β-lactamases, including some class A and class D carbapenemases.
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AAI-101 is a novel extended-spectrum β-lactamase inhibitor with activity against many β-lactamases, including some class A and class D carbapenemases; is currently in clinical development as a combination with cefepime, reduces the MIC50 of cefepime against a collection of 223 cefepime-nonsusceptible isolates of the family Enterobacteriaceae from >64 mg/L to 0.125 mg/L.
Bacterial Infection
Phase 1 Clinical
| M.Wt | 314.32 | |
| Formula | C11H14N4O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Crandon JL, et al. Antimicrob Agents Chemother. 2015 May;59(5):2688-94.
2. Crandon JL, et al. Pathogens. 2015 Aug 18;4(3):620-5.
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