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Chemical Structure : AN-2728
CAS No.: 906673-24-3
Catalog No.: PC-42760Not For Human Use, Lab Use Only.
A potent PDE4 inhibitor with IC50 of 0.49 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $104 | In stock | |
| 50 mg | $208 | In stock | |
| 100 mg | $280 | In stock |
Bulk size, bulk discount!
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A potent PDE4 inhibitor with IC50 of 0.49 uM; also shows inhibition against PDE1A3, PDE3Cat, and PDE7A1; suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines.
Dermatitis
Phase 2 Clinical
| M.Wt | 251.0451 | |
| Formula | C14H10BNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 32 mg/mL |
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| Chemical Name/SMILES |
Benzonitrile, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]- |
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1. Akama T, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2129-32.
2. Nazarian R, et al. Curr Opin Investig Drugs. 2009 Nov;10(11):1236-42.
3. Freund YR, et al. FEBS Lett. 2012 Sep 21;586(19):3410-4.
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