Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : AS 703569
Catalog No.: PC-62560Not For Human Use, Lab Use Only.
Cenisertib (AS 703569;R763) is a novel potent, orally available inhibitor of Aurora kinases, exhibits signifficant anti-proliferative activity against a wide range of tumor cells both in vitro and in vivo (A549 EC50=9 nM).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Cenisertib (AS 703569, R763) is a novel potent, orally available inhibitor of Aurora kinases, exhibits signifficant anti-proliferative activity against a wide range of tumor cells both in vitro and in vivo (A549 EC50=9 nM).
Cenisertib (AS 703569, R763) demonstrates marked inhibition of tumor growth in xenograft models of pancreatic, breast, colon, ovarian, and lung tumors and leukemia.
| M.Wt | 451.54 | |
| Formula | C24H30FN7O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. McLaughlin J, et al. J Cancer Res Clin Oncol. 2010 Jan;136(1):99-113.
2. Illert AL, et al. PLoS One. 2014 Nov 26;9(11):e112318.
3. Peter B, et al. Leukemia. 2017 Nov 29. doi: 10.1038/leu.2017.338.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
