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Chemical Structure : ATV399
Catalog No.: PC-35192Not For Human Use, Lab Use Only.
ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase 9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS.
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ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase 9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS.
ATV399 inhibits cleaved caspase-9 activation and subsequent β-cell apoptosis induced by a combination of IL-1β, IFN-γ and high glucose.
| M.Wt | 465.524 | |
| Formula | C24H23N3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhong L, et al. Br J Pharmacol. 2018 Jun 11. doi: 10.1111/bph.14388.
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