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AZ3

Chemical Structure : AZ3

CAS No.: 1608501-57-0

AZ3 (PI4KB inhibitor 3)

Catalog No.: PC-73080Not For Human Use, Lab Use Only.

AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively).

Physicochemical Properties

M.Wt 499.604
Formula C23H25N5O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-acetyl-N-(4-methyl-5-(6-(phenylsulfonamido)pyridin-2-yl)thiazol-2-yl)piperidine-2-carboxamide

References

1. Michael J Waring, et al. Chem Commun (Camb). 2014 May 25;50(40):5388-90.

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