Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : AZD5718
CAS No.: 2041075-86-7
Catalog No.: PC-36134Not For Human Use, Lab Use Only.
Atuliflapon (AZD-5718, AZD5718) is a novel potent 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 of 6.3 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Atuliflapon (AZD-5718, AZD5718) is a novel potent 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 of 6.3 nM.
Atuliflapon (AZD-5718, AZD5718) exhibits LTB4 inhibition in human whole blood assays with IC50 of 39 nM.
Atuliflapon (AZD-5718, AZD5718) reduces the production of pro-inflammatory and vasoactive leukotrienes both in vitro and in vivo.
| M.Wt | 446.511 | |
| Formula | C24H26N6O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(1R,2R)-2-[4-(3-Methyl-1H-pyrazol-5-yl)benzoyl]-N-(4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl)cyclohexanecarboxamide |
|
1. Ericsson H, et al. Clin Transl Sci. 2018 May;11(3):330-338.
2. Pettersen D, et al. J Med Chem. 2019 Mar 14. doi: 10.1021/acs.jmedchem.8b02004.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
