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Chemical Structure : Angiotensin 1-7
CAS No.: 51833-78-4
Catalog No.: PC-43019Not For Human Use, Lab Use Only.
Angiotensin (1-7) (Ang-(1-7)) is an active heptapeptide of the Renin-angiotensin system (RAS), inhibits purified canine angiotensin converting enzyme (ACE) activity with IC50 of 0.65 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $98 | In stock | |
| 50 mg | $178 | In stock | |
| 100 mg | $328 | In stock | |
| 250 mg | Get quote |
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Angiotensin (1-7) (Ang-(1-7)) is an active heptapeptide of the Renin-angiotensin system (RAS), inhibits purified canine angiotensin converting enzyme (ACE) activity with IC50 of 0.65 uM; augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide, abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2; evokes anti-arrhythmogenic effects in animal models, upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats.
| M.Wt | 899.0048 | |
| Formula | C41H62N12O11 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: ≥ 30.2 mg/mL |
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| Chemical Name/SMILES |
1-7-Angiotensin II, 5-L-isoleucine- |
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1. Li P, et al. Hypertension. 1997 Jan;29(1 Pt 2):394-400.
2. Alzayadneh EM, et al. Cell Signal. 2014 Dec;26(12):3027-35.
3. Averill DB, et al. Circulation. 2003 Oct 28;108(17):2141-6.
4. Costa MA, et al. Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1205-11.
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