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Chemical Structure : BAY85-8501
Catalog No.: PC-60474Not For Human Use, Lab Use Only.
BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.
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BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.
BAY 85-8501 displays no significant inhibition toward 21 related serine proteases (>30 uM).
BAY 85-8501 demonstrates completely prevented the development of lung injury and subsequent inflammation in vivo.
| M.Wt | 474.458 | |
| Formula | C22H17F3N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. von Nussbaum F, et al. ChemMedChem. 2015 Jul;10(7):1163-73.
2. von Nussbaum F, et al. ChemMedChem. 2016 Jan 19;11(2):199-206.
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