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Chemical Structure : BMP signaling agonist sb4
Catalog No.: PC-35964Not For Human Use, Lab Use Only.
BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes.
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BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes; increases the phosphorylation of key second messengers (SMADs-1/5/9) and also increased expression of direct target genes (inhibitors of DNA binding, ID1 and ID3) in canonical BMP signaling.
| M.Wt | 320.204 | |
| Formula | C14H10BrNOS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bradford STJ, et al. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006817.
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