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Chemical Structure : BMS-962212
Catalog No.: PC-62006Not For Human Use, Lab Use Only.
BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM.
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BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM; displays an excellent protease selectivity profile, including thrombin, Factor Xa/VIIa/IXa/XIIa, plasma or tissue kallikrein; shows excellent preclinical efficacy in thrombosis models and aqueous solubility suitable for intravenous administration.
Thrombosis
Phase 1 Clinical
| M.Wt | 659.075 | |
| Formula | C32H28ClFN8O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Pinto DJP, et al. J Med Chem. 2017 Dec 14;60(23):9703-9723.
2. Perera V, et al. Br J Clin Pharmacol. 2018 Jan 18. doi: 10.1111/bcp.13520.
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