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Chemical Structure : BRD-4592
Catalog No.: PC-70214Not For Human Use, Lab Use Only.
A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB).
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A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo.
| M.Wt | 282.318 | |
| Formula | C17H15FN2O | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96.
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