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Chemical Structure : BVT-14225
CAS No.: 376638-65-2
Catalog No.: PC-45407Not For Human Use, Lab Use Only.
BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC50 of 52 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $178 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $458 | In stock | |
| 100 mg | Get quote |
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BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC50 of 52 nM.
BVT-14225 displays >200-fold selectivity over human and murine 11β-HSD2.
BVT-14225 reduces glucose levels in diabetic KKA(y) mice.
| M.Wt | 401.9313 | |
| Formula | C16H20ClN3O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 27 mg/mL |
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| Chemical Name/SMILES |
4-Thiazoleacetamide, 2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-N,N-diethyl- |
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1. Barf T, et al. J Med Chem. 2002 Aug 29;45(18):3813-5.
2. Vicker N, et al. J Steroid Biochem Mol Biol. 2007 May;104(3-5):123-9.
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