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Chemical Structure : BVT-2733
CAS No.: 376640-41-4
Catalog No.: PC-45406Not For Human Use, Lab Use Only.
BVT-2733 (BVT2733) is a non-steroidal, isoform-selective inhibitor of mouse 11β-HSD1 with Ki of 1 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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BVT-2733 (BVT2733) is a non-steroidal, isoform-selective inhibitor of mouse 11β-HSD1 with Ki of 1 uM.
BVT-2733 displays >20-fold selectivity over 11β-HSD2.
BVT-2733 lowers hepatic PEPCK and glucose-6-phosphatase mRNA, blood glucose and serum insulin concentrations in a hyperglycaemic and hyperinsulinaemic mouse model.
| M.Wt | 428.9566 | |
| Formula | C17H21ClN4O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzenesulfonamide, 3-chloro-2-methyl-N-[4-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-2-thiazolyl]- |
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1. Alberts P, et al. Diabetologia. 2002 Nov;45(11):1528-32.
2. Alberts P, et al. Endocrinology. 2003 Nov;144(11):4755-62.
3. Wang L, et al. PLoS One. 2012;7(7):e40056.
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