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Bisantrene

Chemical Structure : Bisantrene

CAS No.: 78186-34-2

Bisantrene (CL216942)

Catalog No.: PC-42280Not For Human Use, Lab Use Only.

A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin.

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Biological Activity

A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.

Physicochemical Properties

M.Wt 398.46368
Formula C22H22N8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 133.33 mg/mL

Chemical Name/SMILES

9,10-Anthracenedicarboxaldehyde, 9,10-bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone]

References

1. Citarella RV, et al. Cancer Res. 1982 Feb;42(2):440-4.

2. Von Hoff DD, et al. Cancer Chemother Pharmacol. 1981;6(2):141-4.

3. Von Hoff DD, et al. Cancer Res. 1982 Feb;42(2):440-4.

4. Lown JW, et al. Mol Pharmacol. 1984 Jan;25(1):178-84.

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