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Chemical Structure : CI-976
CAS No.: 114289-47-3
Catalog No.: PC-62403Not For Human Use, Lab Use Only.
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $258 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | $728 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
CI-976 decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits.
| M.Wt | 393.568 | |
| Formula | C23H39NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide |
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1. Field FJ, et al. Lipids. 1991 Jan;26(1):1-8.
2. O'Brien PM, et al. J Med Chem. 1994 Jun 10;37(12):1810-22.
3. Krause BR, et al. J Lipid Res. 1993 Feb;34(2):279-94.
4. Baba T, et al. Mol Cell Biochem. 2013 Apr;376(1-2):151-61.
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