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Chemical Structure : CL 316243 disodium
Catalog No.: PC-62016Not For Human Use, Lab Use Only.
CL 316243 is a potent, highly selective, orally active β3-adrenoceptor agonist with EC50 of 3 nM.
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CL 316243 is a potent, highly selective, orally active β3-adrenoceptor agonist with EC50 of 3 nM.
CL 316243 displays >10000-fold selective over β1 and β2 receptors。
CL 316243 significantly increases brown adipose tissue thermogenesis and resting metabolic rate in mice, also increases the concentration of insulin receptors and decreases the levels of serum insulin and blood glucose during the glucose overloading test.
| M.Wt | 465.8 | |
| Formula | C20H18ClNNa2O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Berlan M, et al. J Pharmacol Exp Ther. 1994 Mar;268(3):1444-51.
2. Himms-Hagen J, et al. Am J Physiol. 1994 Apr;266(4 Pt 2):R1371-82.
3. Yoshida T, et al. Life Sci. 1994;54(7):491-8.
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