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Chemical Structure : CY-09
CAS No.: 1073612-91-5
Catalog No.: PC-35137Not For Human Use, Lab Use Only.
CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $158 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity.
CY-09 suppresses NLRP3 inflammasome assembly and activation, shows remarkable therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes.
| M.Wt | 423.424 | |
| Formula | C19H12F3NO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzoic acid, 4-[[4-oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]- |
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1. Jiang H, et al. J Exp Med. 2017 Nov 6;214(11):3219-3238.
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