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Cridanimod

Chemical Structure : Cridanimod

CAS No.: 38609-97-1

Cridanimod (10-carboxymethyl-9-acridanone;10-CMA;XBIO-101)

Catalog No.: PC-60186Not For Human Use, Lab Use Only.

Cridanimod (10-carboxymethyl-9-acridanone, 10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

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Biological Activity

Cridanimod (10-carboxymethyl-9-acridanone, 10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route; displays extraordinary activity in phosphorylating IRF3 in the murine system; also increases progesterone receptor (PrR) expression in endometrial tissue.

Ovarian Cancer

Phase 2 Clinical

Physicochemical Properties

M.Wt 253.25
Formula C15H11NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(9-oxoacridin-10-yl)acetic acid

References

1. Cavlar T, et al. EMBO J. 2013 May 15;32(10):1440-50.

2. Zhang H, et al. Sci Rep. 2015 Dec 16;5:18035.

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