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Chemical Structure : Delgocitinib
CAS No.: 1263774-59-9
Catalog No.: PC-60508Not For Human Use, Lab Use Only.
Delgocitinib (JTE-052, LEO 124249) is a potent, selective, orally active, pan-JAK inhibitor with IC50 of 2.8, 2.6, 13 and 58 nM for JAK1,2,3 and Tyk2, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $458 | In stock | |
| 10 mg | $758 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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| M.Wt | 310.361 | |
| Formula | C16H18N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)- 1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile |
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1. Tanimoto A, et al. Inflamm Res. 2015 Jan;64(1):41-51.
2. Amano W, et al. J Allergy Clin Immunol. 2015 Sep;136(3):667-677.e7.
3. Tanimoto A, et al. BMC Musculoskelet Disord. 2015 Nov 6;16:339.
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