Chemical Structure : Fiacitabine
CAS No.: 69123-90-6
Catalog No.: PC-45855Not For Human Use, Lab Use Only.
A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent.
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A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively, shows minimal cytotoxicity; more potent than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine.
HSV Infection
Phase 2 Discontinued
M.Wt | 371.1042 | |
Formula | C9H11FIN3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 37 mg/mL |
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Chemical Name/SMILES |
2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-iodo- |
1. Lopez C, et al. Antimicrob Agents Chemother. 1980 May;17(5):803-6.
2. Allaudeen HS, et al. J Biol Chem. 1982 Oct 25;257(20):11879-82.
3. Schinazi RF, et al. Antimicrob Agents Chemother. 1983 Jul;24(1):95-103.
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