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Fosmanogepix

Chemical Structure : Fosmanogepix

CAS No.: 2091769-17-2

Fosmanogepix (APX001 prodrug;E1210 prodrug)

Catalog No.: PC-35452Not For Human Use, Lab Use Only.

Fosmanogepix (APX001 prodrug) is a novel antifungal agent, the prodrug form of APX001, which inhibits the fungal protein Gwt1..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Fosmanogepix (APX001 prodrug) is a novel antifungal agent, the prodrug form of APX001, which inhibits the fungal protein Gwt1.

Physicochemical Properties

M.Wt 468.406
Formula C22H21N4O6P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Pyridinium, 2-amino-1-[(phosphonooxy)methyl]-3-[3-[[4-[(2-pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-, inner salt

References

1. Hager CL, et al. Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e02319-17.

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