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Chemical Structure : GLPG-0492
Catalog No.: PC-45421Not For Human Use, Lab Use Only.
A novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM.
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A novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM; exhibits anabolic activity on muscle, strongly dissociated from the androgenic activity on prostate in a classical model of orchidectomized rat; shows a potential treatment for Duchenne muscular dystrophy (DMD).
Other Indication
Phase 1 Clinical
| M.Wt | 389.328 | |
| Formula | C19H14F3N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nique F, et al. J Med Chem. 2012 Oct 11;55(19):8236-47.
2. Cozzoli A, et al. Pharmacol Res. 2013 Jun;72:9-24.
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