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Chemical Structure : GSK-2807
Catalog No.: PC-70109Not For Human Use, Lab Use Only.
GSK-2807 (GSK 2807, GSK2807) is a potent and selective, SAM-competitive inhibitor of SMYD3 with Ki of 14 nM.
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GSK-2807 (GSK 2807, GSK2807) is a potent and selective, SAM-competitive inhibitor of SMYD3 with Ki of 14 nM; displays 24-fold selectivity over SMYD2, and a panel of PRMTs including: PRMT1, PRMT4, PRMT5, NSD2, NSD3, DOT1L, G9a, and ASH1L.
| M.Wt | 452.516 | |
| Formula | C19H32N8O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Van Aller GS, et al. Structure. 2016 May 3;24(5):774-81.
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