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GSK-812

Chemical Structure : GSK-812

CAS No.: 630407-66-8

GSK-812 (GSK812)

Catalog No.: PC-61812Not For Human Use, Lab Use Only.

GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors.

Physicochemical Properties

M.Wt 471.996
Formula C25H26ClNO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-[4-(4-chloro-benzyloxy)-benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

References

1. Baranov P, et al. J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422.

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