Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Glumetinib
CAS No.: 1642581-63-2
Catalog No.: PC-60074Not For Human Use, Lab Use Only.
Glumetinib (SCC 244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Glumetinib (SCC 244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM.
Glumetinib (SCC 244) displays high selectivity versus 312 other tested protein kinases.
Glumetinib (SCC 244) profoundly and specifically inhibits c-Met signal transduction and suppresses the c-Met-dependent neoplastic phenotype of tumor and endothelial cells.
Glumetinib (SCC 244) exhibits robust in vivo antitumor activity in NSCLC and hepatocellular carcinoma models.
| M.Wt | 459.488 | |
| Formula | C21H17N9O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6-(1-Methyl-1H-pyrazol-4-yl)-1-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]sulfonyl]-1H-pyrazolo[4,3-b]pyridine |
|
1. Ai J, et al. Mol Cancer Ther. 2017 Dec 13. pii: molcanther.0368.2017.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
