Chemical Structure : HG-7-92-01
CAS No.: 1315355-93-1
Catalog No.: PC-61640Not For Human Use, Lab Use Only.
HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.
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HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.
M.Wt | 537.587 | |
Formula | C29H30F3N5O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO (5.4 mg/mL) |
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Chemical Name/SMILES |
3-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methylbenzamide |
1. Hellwig S, et al. Chem Biol. 2012 Apr 20;19(4):529-40.
2. Weir MC, et al. PLoS One. 2017 Jul 20;12(7):e0181178.
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