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Chemical Structure : HPGDS inhibitor 1
CAS No.: 1033836-12-2
Catalog No.: PC-42585Not For Human Use, Lab Use Only.
HPGDS inhibitor 1 is a potent, selective, oral hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with enzyme IC50 of 0.6 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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HPGDS inhibitor 1 is a potent, selective, oral hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with enzyme IC50 of 0.6 nM.
HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5 LOX (IC50>10 uM).
HPGDS inhibitor 1 reduces the antigen-induced response in vivo.
| M.Wt | 381.3673 | |
| Formula | C19H19F4N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-Pyridinecarboxamide, 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]- |
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1. Carron CP, et al. ACS Med Chem Lett. 2010 Feb 2;1(2):59-63.
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