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Chemical Structure : IAA-94
CAS No.: 54197-31-8
Catalog No.: PC-43155Not For Human Use, Lab Use Only.
IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | Get quote |
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IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM.
IAA-94 significantly suppresses IGF-I-induced VSMC proliferation, also blocks cell swelling evoked glutamate release from primary microglia and MLS-9 cells.
IAA-94 effectively reduces IFNgamma-induced NO production in microglial BV2 cells.
| M.Wt | 357.2284 | |
| Formula | C17H18Cl2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Acetic acid, 2-[[(2R)-6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl]oxy]- |
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1. Landry DW, et al. J Gen Physiol. 1987 Dec;90(6):779-98.
2. Cheng G, et al. Cardiovasc Res. 2007 Jan 1;73(1):198-207.
3. Schlichter LC, et al. Channels (Austin). 2011 Mar-Apr;5(2):128-37.
4. Kjaer K, et al. Brain Res. 2009 Jul 24;1281:15-24.
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