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Chemical Structure : INF39
CAS No.: 866028-26-4
Catalog No.: PC-35385Not For Human Use, Lab Use Only.
INF39 (NLRP3 inhibitor INF39) is a nontoxic, irreversible, orally available NLRP3 inhibitor that inhibits NLRP3 ATPase and decreases interleukin-1β release from macrophages.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $108 | In stock | |
| 25 mg | $258 | In stock | |
| 100 mg | $548 | In stock | |
| 500 mg | Get quote |
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INF39 (NLRP3 inhibitor INF39) is a nontoxic, irreversible, orally available NLRP3 inhibitor that inhibits NLRP3 ATPase and decreases interleukin-1β release from macrophages; significantly inhibit ATP- and nigericin-induced IL-1β release in mouse bone marrow derived macrophages (BMDM) at 10 uM, reduces colonic myeloperoxidase, IL-1β, and TNF Levels in DNBS-treated rats.
| M.Wt | 224.684 | |
| Formula | C12H13ClO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Ethyl 2-(2-chlorobenzyl)acrylate |
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1. Cocco M, et al. J Med Chem. 2017 May 11;60(9):3656-3671.
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