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Chemical Structure : ITX-5061 hydrochloride
CAS No.: 1252679-52-9
Catalog No.: PC-62103Not For Human Use, Lab Use Only.
ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $278 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels.
ITX-5061 inhibits SR-BI-dependent uptake of HDL-CE in transfected cells, decreases the fractional catabolic rate of HDL-CE and reduced its hepatic uptake in mice.
ITX-5061 inhibits HCVcc and HCVpp infection of primary human hepatocytes and/or human hepatoma cell lines and has minimal effects on HCV RNA replication.
| M.Wt | 620.158 | |
| Formula | C30H38ClN3O7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide hydrochloride |
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1. Masson D, et al. Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2054-60.
2. Zhu H, et al. J Infect Dis. 2012 Feb 15;205(4):656-62.
3. Syder AJ, et al. J Hepatol. 2011 Jan;54(1):48-55.
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