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Chemical Structure : Ibutamoren mesylate
CAS No.: 159752-10-0
Catalog No.: PC-45866Not For Human Use, Lab Use Only.
A non-peptidic, poten and selective, orally-active agonist of the ghrelin receptor (GHSR) with EC50 of 1.3 nM (releases GH from rat pituitary cells).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $79.2 | In stock | |
| 50 mg | $336 | In stock |
Bulk size, bulk discount!
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A non-peptidic, poten and selective, orally-active agonist of the ghrelin receptor (GHSR) with EC50 of 1.3 nM (releases GH from rat pituitary cells); significantly increased peak GH concentrations 20.4-fold at 0.25 mg/kg in beagles; has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
Growth Hormone Deficiency
Phase 2 Clinical
| M.Wt | 624.7692 | |
| Formula | C28H40N4O8S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, methanesulfonate (1:1) |
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1. Patchett AA, et al. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7001-5.
2. Jacks T, et al. Endocrinology. 1996 Dec;137(12):5284-9.
3. Copinschi G, et al. Neuroendocrinology. 1997 Oct;66(4):278-86.
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