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Chemical Structure : Isobavachalcone
CAS No.: 20784-50-3
Catalog No.: PC-43370Not For Human Use, Lab Use Only.
Isobavachalcone (Corylifolinin, Isobacachalcone) is a chalcone constituent of Angelica keiskei that can induce apoptosis in several cancer cells, also shows activity against multidrug-resistant (MDR) Gram-negative bacterial isolates.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $75 | In stock | |
| 25 mg | $195 | In stock | |
| 100 mg | $525 | In stock | |
| 500 mg | Get quote |
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Isobavachalcone (Corylifolinin, Isobacachalcone) is a chalcone constituent of Angelica keiskei that can induce apoptosis in several cancer cells, also shows activity against multidrug-resistant (MDR) Gram-negative bacterial isolates; significantly reduces pro-caspase-3 and pro-caspase-9, and subsequently increases the level of cleaved caspase-3 and cleaved caspase-9 in neuroblastoma cell lines also exhibiting deletions of the major efflux pump components (AcrAB, TolC).
| M.Wt | 324.3704 | |
| Formula | C20H20O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 11 mg/mL |
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| Chemical Name/SMILES |
2-Propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)- |
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1. Nishimura R, et al. Biol Pharm Bull. 2007 Oct;30(10):1878-83.
2. Kuete V, et al. Antimicrob Agents Chemother. 2010 May;54(5):1749-52.
3. Jing H, et al. Cancer Lett. 2010 Aug 28;294(2):167-77.
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