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Chemical Structure : JBJ-01-162-04
Catalog No.: PC-35947Not For Human Use, Lab Use Only.
JBJ-01-162-04 is a small molecule targeting the flavivirus E protein with broad-spectrum activity, shows activity against DENV in the infectivity assay with IC90 of 0.1 uM.
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JBJ-01-162-04 is a small molecule targeting the flavivirus E protein with broad-spectrum activity, shows activity against DENV in the infectivity assay with IC90 of 0.1 uM.
JBJ-01-162-04 binds to DENV2 E protein (sE2) with Kd of 1.4 uM, reduces DENV viral burden in vivo.
| M.Wt | 437.382 | |
| Formula | C22H14F3N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li PC, et al. ACS Infect Dis. 2019 Jan 4. doi: 10.1021/acsinfecdis.8b00322.
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