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Chemical Structure : Kinesore
Catalog No.: PC-62648Not For Human Use, Lab Use Only.
Kinesore is a small molecule activator of kinesin-1 that inhibits KLC2-SKIP interaction with IC50 of 101 uM, Ki of 49 uM.
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Kinesore is a small molecule activator of kinesin-1 that inhibits KLC2-SKIP interaction with IC50 of 101 uM, Ki of 49 uM; inhibits kinesin-1 interactions with short linear peptide motifs found in organelle-specific cargo adaptors, yet activates kinesin-1's function of controlling microtubule dynamics in cells; induces the remodeling of the microtubule network.
| M.Wt | 536.18 | |
| Formula | C20H16Br2N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Randall TS, et al. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13738-13743.
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