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Chemical Structure : LDN-214117
CAS No.: 1627503-67-6
Catalog No.: PC-45058Not For Human Use, Lab Use Only.
LDN-214117 (LDN214117) is a potent and selective ALK2 inhibitor with a biochemical IC50 of 24 nM, a cell-based IC50 for BMP6 of 100 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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LDN-214117 (LDN214117) is a potent and selective ALK2 inhibitor with a biochemical IC50 of 24 nM, a cell-based IC50 for BMP6 of 100 nM.
LDN-214117 displays 164-fold selectivity for BMP6 versus TGF-β1.
LDN-214117 is a highly selective probe of BMP-mediated cellular physiology.
| M.Wt | 419.5161 | |
| Formula | C25H29N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Piperazine, 1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]- |
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1. Mohedas AH, et al. J Med Chem. 2014 Oct 9;57(19):7900-15.
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