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Chemical Structure : LGD-2226
Catalog No.: PC-35143Not For Human Use, Lab Use Only.
LGD-2226 (LGD2226) is an orally active, selective androgen receptor modulator (SARM) with binding Ki of 1 nM, >1000-fold selectivity over GR,PR, MR and ER.
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LGD-2226 (LGD2226) is an orally active, selective androgen receptor modulator (SARM) with binding Ki of 1 nM, >1000-fold selectivity over GR,PR, MR and ER; LGD2226 is fully active in cell-based models of bone and muscle, exhibits anabolic activity on muscle and bone with reduced impact on prostate growth in rodent models; LGD2226 is also efficacious in a sex-behavior model in male rats measuring mounts, intromissions, ejaculations, and copulation efficiency.
Osteoporosis
Discontinued
| M.Wt | 392.225 | |
| Formula | C14H9F9N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Miner JN, et al. Endocrinology. 2007 Jan;148(1):363-73.
2. van Oeveren A, et al. J Med Chem. 2006 Oct 19;49(21):6143-6.
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