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Chemical Structure : LY-2562175
CAS No.: 1103500-20-4
Catalog No.: PC-60079Not For Human Use, Lab Use Only.
LY-2562175 (LY2562175, LY 2562175) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 50 mg | $688 | In stock | |
| 100 mg | $958 | In stock | |
| 250 mg | $1580 | In stock | |
| 1 g | Get quote |
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LY-2562175 (LY2562175, LY 2562175) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM.
LY-2562175 does not promote transcriptional activation of other nuclear receptor, such as GR, PR, MR and AR (EC50>10 uM).
LY-2562175 lowers LDL and triglycerides while raising HDL in preclinical species.
| M.Wt | 540.441 | |
| Formula | C28H27Cl2N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
100 mM in DMSO (54 mg/mL) |
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| Chemical Name/SMILES |
6-(4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid |
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1. Genin MJ, et al. J Med Chem. 2015 Dec 24;58(24):9768-72.
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