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Chemical Structure : Leucettamine B
Catalog No.: PC-63478Not For Human Use, Lab Use Only.
Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM)..
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Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
| M.Wt | 245.238 | |
| Formula | C12H11N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chan GW, et al. J Nat Prod. 1993 Jan;56(1):116-21.
2. Debdab M, et al. J Med Chem. 2011 Jun 23;54(12):4172-86.
3. Tahtouh T, et al. J Med Chem. 2012 Nov 8;55(21):9312-30.
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