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MIN-101

Chemical Structure : MIN-101

CAS No.: 359625-79-9

MIN-101 (Roluperidone;CYR-101;MT-210;MIN101)

Catalog No.: PC-61105Not For Human Use, Lab Use Only.

MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist with Ki of 7.53 nM and 8.19 nM respectively.
MIN-101 (Roluperidone, CYR-101, MT-210) shows  with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.

Physicochemical Properties

M.Wt 366.429
Formula C22H23F2N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[[1-[2-(4-Fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro-1H-isoindol-1-one

References

1. Davidson M, et al. Am J Psychiatry. 2017 Dec 1;174(12):1195-1202.

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