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MK-204

Chemical Structure : MK-204

CAS No.: 1959605-73-2

MK-204 (MK204)

Catalog No.: PC-62883Not For Human Use, Lab Use Only.

MK-204 is a potent, selective AKR1B10 inhibitor with IC50 of 80 nM, shows high selective (270-fold) over AKR1B1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MK-204 is a potent, selective AKR1B10 inhibitor with IC50 of 80 nM, shows high selective (270-fold) over AKR1B1; a lead compound targeting the distinct AKR1B10 specificity pocket and with a strong X-bond.

Physicochemical Properties

M.Wt 714.221
Formula C16H9Br5ClNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Acetic acid, 2-[5-chloro-2-[[[(2,3,4,5,6-pentabromophenyl)methyl]amino]carbonyl]phenoxy]-

References

1. Cousido-Siah A, et al. ACS Chem Biol. 2016 Oct 21;11(10):2693-2705.

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