You are here:Home-Chemical Inhibitors & Agonists-PI3K/Akt/mTOR Pathway-AMPK-MK-3903
MK-3903

Chemical Structure : MK-3903

CAS No.: 1219737-12-8

MK-3903 (MK3903)

Catalog No.: PC-62013Not For Human Use, Lab Use Only.

MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM.

Packing Price Stock Quantity
10 mg $138 In stock
25 mg $218 In stock
50 mg $368 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM.
MK-3903 activates 10 of the 12 phosphorylated AMPK (pAMPK) complexes with EC50s of 8-40 nM.
MK-3903 improves lipid metabolism and insulin sensitization in mice.

Physicochemical Properties

M.Wt 454.91
Formula C27H19ClN2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 100 mM (45.5 mg/mL)

Chemical Name/SMILES

5-[(5-[1,1'-Biphenyl]-4-yl-6-chloro-1H-benzimidazol-2-yl)oxy]-2-methylbenzoic acid

References

1. Lan P, et al. J Med Chem. 2017 Nov 9;60(21):9040-9052.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: