Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ML-240
CAS No.: 1346527-98-7
Catalog No.: PC-45717Not For Human Use, Lab Use Only.
ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | $398 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
ML240 blocks degradation of p97-dependent proteasome substrate with an IC50 of 0.9 uM.
ML240 induces caspases 3 and 7 and potently blocked proliferation in HCT15 and SW403 cells.
| M.Wt | 396.4445 | |
| Formula | C23H20N6O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
DMSO: 16.5 mg/mL |
|
| Chemical Name/SMILES |
4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)- |
|
1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.
3. Bastola P, et al. Mol Oncol. 2016 Dec;10(10):1559-1574.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
