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Methyliodobikinin

Chemical Structure : Methyliodobikinin

CAS No.: 1186336-04-8

Methyliodobikinin

Catalog No.: PC-63239Not For Human Use, Lab Use Only.

Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro; activates brassinosteroid (BR) signalling and mimic BR action, 3.4 times more active in vivo than bikinin.

Physicochemical Properties

M.Wt 334.113
Formula C10H11IN2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methyl 4-((5-iodopyridin-2-yl)amino)-4-oxobutanoate

References

1. Rozhon W, et al. BMC Plant Biol. 2014 Jun 19;14:172.

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