Chemical Structure : Minnelide
Catalog No.: PC-70029Not For Human Use, Lab Use Only.
Minnelide is a water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival, induces and promotes apoptosis.
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Minnelide is a water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival, induces and promotes apoptosis.
Minnelide efficiently downregulates both CD133(-) and CD133(+) population in the tumors, resulting in a 60% decrease in tumor volume.
Minnelide also is very effective as a therapeutic option against Castration Resistant Prostate Cancer (CRPC).
M.Wt | 514.374 | |
Formula | C21H25Na2O10P | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Chugh R, et al. Sci Transl Med. 2012 Oct 17;4(156):156ra139.
2. Banerjee S, et al. Clin Cancer Res. 2014 May 1;20(9):2388-99.
3. Isharwal S, et al. Prostate. 2017 May;77(6):584-596.
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