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Chemical Structure : NSC654259
Catalog No.: PC-60868Not For Human Use, Lab Use Only.
NSC654259 is novel small molecule Wnt signaling inhibitor that targets the cysteine-rich domain of Frizzled, specifically binds to the Wnt binding site on the Frizzled 8 (FZD8) cysteine-rich domain with Kd of 2.9 uM, IC50 of 5.7 uM.
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NSC654259 is novel small molecule Wnt signaling inhibitor that targets the cysteine-rich domain of Frizzled, specifically binds to the Wnt binding site on the Frizzled 8 (FZD8) cysteine-rich domain with Kd of 2.9 uM, IC50 of 5.7 uM.
| M.Wt | 535.783 | |
| Formula | C21H20BrClN6O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lee HJ, et al. J Biol Chem. 2015 Dec 18;290(51):30596-606.
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