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PD1-PDL1 inhibitor 1

Chemical Structure : PD1-PDL1 inhibitor 1

CAS No.: 1675201-83-8

PD1-PDL1 inhibitor 1 (PD-1/PD-L1 inhibitor 1)

Catalog No.: PC-45776Not For Human Use, Lab Use Only.

PD1-PDL1 inhibitor 1 (CAS 1675201-83-8) is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay..

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Biological Activity

PD1-PDL1 inhibitor 1 (CAS 1675201-83-8) is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.

Physicochemical Properties

M.Wt 475.576
Formula C29H33NO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 29 mg/mL

Chemical Name/SMILES

2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)-

References

1. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).

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