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PD1-PD L1 inhibitor Polaris

Chemical Structure : PD1-PD L1 inhibitor Polaris

CAS No.: 2201132-36-5

PD1-PD L1 inhibitor Polaris

Catalog No.: PC-35244Not For Human Use, Lab Use Only.

PD1-PD L1 inhibitor Polaris is a novel potent, small molecule inhibitor of PD-1/PD-L1 interaction (IC50=0.1-10 nM in ELISA assays) with anti-cancer activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PD1-PD L1 inhibitor Polaris is a novel potent, small molecule inhibitor of PD-1/PD-L1 interaction (IC50=0.1-10 nM in ELISA assays) with anti-cancer activity.

Physicochemical Properties

M.Wt 834.646
Formula C42H46Br2N2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,2'S)-1,1'-(((((2,2'-dimethyl-[1,1'-biphenyl]-3,3'-diyl)bis(methylene))bis(oxy))bis(3-bromo-4,1-phenylene))bis(methylene))bis(piperidine-2-carboxylic acid)

References

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