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Chemical Structure : PF-00446687 hydrochloride
Catalog No.: PC-60213Not For Human Use, Lab Use Only.
PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM.
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PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM; displays >100-fold selectivity over MC1R/
Sexual Dysfunction
Phase 2 Clinical
| M.Wt | 507.06 | |
| Formula | C28H37ClF2N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lansdell MI, et al. J Med Chem. 2010 Apr 22;53(8):3183-97.
2. Modi ME, et al. Neuropsychopharmacology. 2015 Jul;40(8):1856-65.
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