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Chemical Structure : PHY34
Catalog No.: PC-35620Not For Human Use, Lab Use Only.
PHY34 is a potent autophagy inhibitor with cytotoxic effects by inhibiting autophagy at a late stage (MDA-MB-435 IC50=23 nM, MDA-MB-231 IC50=5.2 nM).
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PHY34 is a potent autophagy inhibitor with cytotoxic effects by inhibiting autophagy at a late stage (MDA-MB-435 IC50=23 nM, MDA-MB-231 IC50=5.2 nM).
PHY34 disrupts lysosomal function, significantly inhibits the growth of cancer cell lines in hollow fibers, as well as reduces ovarian tumor burden in a xenograft model.
| M.Wt | 522.506 | |
| Formula | C28H26O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Young AN, et al. Mol Cancer Ther. 2018 Jul 17. pii: molcanther.1195.2017.
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